Linker Information
General Information of This Linker
| Linker ID |
LIN00061
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| Linker Name |
(Z)-N'-(2-hydroxyethylidene)-6-(3-mercapto-2,5-dioxopyrrolidin-1-yl)hexanehydrazide
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| Linker Type |
PH-Sensitive linkers
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| Structure |
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| Formula |
C12H19N3O4S
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| #Ro5 Violations (Lipinski): 0 | Molecular Weight (mw) | 301.368 | ||||
| Lipid-water partition coefficient (xlogp) | -0.3016 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 3 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 6 | |||||
| Rotatable Bond Count (rotbonds) | 8 | |||||
| Canonical smiles |
O=C(CCCCCN1C(=O)CC(S)C1=O)NN=CCO
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| InChI |
InChI=1S/C12H19N3O4S/c16-7-5-13-14-10(17)4-2-1-3-6-15-11(18)8-9(20)12(15)19/h5,9,16,20H,1-4,6-8H2,(H,14,17)/b13-5-
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| InChIKey |
VWBYZCVBANWODJ-ACAGNQJTSA-N
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Each Peptide-drug Conjugate Related to This Linker