Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01196
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| PDC Name |
Tuftsin (liberated from the Fc domain of the heavy chain of IgG 1 - 1,4-dihydroxyanthraquinone (quinizarin) derivative conjugate 3
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Tuftsin (liberated from the Fc domain of the heavy chain of IgG 1
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Peptide Info | ||||
| Drug Name |
1,4-dihydroxyanthraquinone (quinizarin) derivative
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1); Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Formula |
C40H55N9O10
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 821.933 | ||||
| Lipid-water partition coefficient (xlogp) | -0.3025 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 10 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 12 | |||||
| Rotatable Bond Count (rotbonds) | 20 | |||||