Receptor Information
General Information of This Receptor
| Receptor ID |
REC00021
|
|||||
|---|---|---|---|---|---|---|
| Receptor Name |
D(2) dopamine receptor; D(3) dopamine receptor (DRD2; DRD3)
|
|||||
| Gene Name |
DRD2; DRD3
|
|||||
| Gene ID | ||||||
| Synonym |
Dopamine D2 receptor
|
|||||
| Sequence |
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA VNPIIYTTFNIEFRKAFLKILHC
Click to Show/Hide
|
|||||
| Family |
the G-protein coupled receptor 1 family
|
|||||
| Function |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase . Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
Click to Show/Hide
|
|||||
| Uniprot Entry | ||||||
| HGNC ID | ||||||
| KEGG ID | ||||||
Each Peptide-drug Conjuate AND It's Component Related to This Receptor
Full List of The PDC Related to This Receptor
Fallypride
| PDC Info | PDC Name | Drug | Target | Linker |
|---|---|---|---|---|
|
18F-fallypride
|
Fluorine-18
|
Human Deoxyribonucleic acid (hDNA)
|
Alkane
|