Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00431
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| PDC Name |
Model peptide 1 - Camptothecin conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Model peptide 1
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Peptide Info | ||||
| Drug Name |
Camptothecin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Triazole
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Linker Info | ||||
| Formula |
C116H150N28O29S3
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 2496.844 | ||||
| Lipid-water partition coefficient (xlogp) | -1.5077 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 25 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 38 | |||||
| Rotatable Bond Count (rotbonds) | 72 | |||||