Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00530
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| PDC Name |
[C(WR)4K2(b-A)] - Doxorubicin & Curcumine conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
[C(WR)4K2(b-A)]
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Peptide Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Propanamide
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Linker Info | ||||
| Peptide Modified Type |
Cyclization modification
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| Formula |
C147H184N32O33S2
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 2991.414 | ||||
| Lipid-water partition coefficient (xlogp) | 4.33947 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 35 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 40 | |||||
| Rotatable Bond Count (rotbonds) | 64 | |||||