Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00531
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| PDC Name |
[C(WR)4K2(b-A)] - Doxorubicin conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
[C(WR)4K2(b-A)]
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Peptide Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Propanamide
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Linker Info | ||||
| Peptide Modified Type |
Cyclization modification
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| Formula |
C121H160N32O25S2
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 2526.944 | ||||
| Lipid-water partition coefficient (xlogp) | -0.05433 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 33 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 33 | |||||
| Rotatable Bond Count (rotbonds) | 51 | |||||