Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00543
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| PDC Name |
Penetratine 1 - Methotrexate conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Penetratine 1
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Peptide Info | ||||
| Drug Name |
Methotrexate
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Drug Info | ||||
| Therapeutic Target |
Reduced folate transporter (SLC19A1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Formula |
C138H205N45O27
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 2926.446 | ||||
| Lipid-water partition coefficient (xlogp) | -6.1027 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 39 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 39 | |||||
| Rotatable Bond Count (rotbonds) | 97 | |||||