Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00547
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| PDC Name |
Penetratine 3 - Methotrexate conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Penetratine 3
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Peptide Info | ||||
| Drug Name |
Methotrexate
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Drug Info | ||||
| Therapeutic Target |
Reduced folate transporter (SLC19A1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Formula |
C119H179N41O23
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 2552.005 | ||||
| Lipid-water partition coefficient (xlogp) | -5.5935 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 35 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 35 | |||||
| Rotatable Bond Count (rotbonds) | 85 | |||||