Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00600
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| PDC Name |
Somatostatin backbone cyclic analog - Camptothecin conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Somatostatin backbone cyclic analog
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Peptide Info | ||||
| Drug Name |
Camptothecin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Butyramide
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Linker Info | ||||
| Peptide Modified Type |
Cyclization modification
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| Formula |
C91H100N16O16S2
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1738.031 | ||||
| Lipid-water partition coefficient (xlogp) | 4.8669 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 14 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 21 | |||||
| Rotatable Bond Count (rotbonds) | 26 | |||||