Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00601
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| PDC Name |
Somatostatin backbone cyclic analog - Chlorambucil conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Somatostatin backbone cyclic analog
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Peptide Info | ||||
| Drug Name |
Chlorambucil
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Butyramide
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Linker Info | ||||
| Peptide Modified Type |
Cyclization modification
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| Formula |
C84H103Cl2N15O12S2
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 1649.881 | ||||
| Lipid-water partition coefficient (xlogp) | 5.4629 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 14 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 16 | |||||
| Rotatable Bond Count (rotbonds) | 33 | |||||