Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01003
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| PDC Name |
Activable cell-penetrating peptide (ACCP) - Doxorubicin conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Activable cell-penetrating peptide (ACCP)
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Peptide Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Succinimide
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Linker Info | ||||
| Formula |
C145H230N56O50S
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 3589.844 | ||||
| Lipid-water partition coefficient (xlogp) | -25.26259 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 58 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 56 | |||||
| Rotatable Bond Count (rotbonds) | 112 | |||||