Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01212
|
|||||
|---|---|---|---|---|---|---|
| PDC Name |
Tripeptide 52 - Methotrexate conjugate
|
|||||
| PDC Status |
Investigative
|
|||||
| Structure |
|
|||||
| Peptide Name |
Tripeptide 52
|
Peptide Info | ||||
| Drug Name |
Methotrexate
|
Drug Info | ||||
| Therapeutic Target |
Reduced folate transporter (SLC19A1)
|
Target Info | ||||
| Linker Name |
Undisclosed
|
|||||
| Formula |
C34H51N11O8
|
|||||
| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 741.851 | ||||
| Lipid-water partition coefficient (xlogp) | -0.3166 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 6 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 16 | |||||
| Rotatable Bond Count (rotbonds) | 25 | |||||