Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01620
|
|||||
|---|---|---|---|---|---|---|
| PDC Name |
CVKRGLKLRHVRPRVTRMDV - Doxorubicin conjugate
|
|||||
| PDC Status |
Investigative
|
|||||
| Structure |
|
|||||
| Peptide Name |
CVKRGLKLRHVRPRVTRMDV
|
Peptide Info | ||||
| Drug Name |
Doxorubicin
|
Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
|
Target Info | ||||
| Linker Name |
4-Maleimidobutyric acid
|
Linker Info | ||||
| Formula |
C138H223N41O38S2
|
|||||
| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 3128.685 | ||||
| Lipid-water partition coefficient (xlogp) | -9.57465 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 46 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 47 | |||||
| Rotatable Bond Count (rotbonds) | 95 | |||||