Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01878
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| PDC Name |
Dipeptide 46 - Chlorambucil conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Dipeptide 46
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Peptide Info | ||||
| Drug Name |
Chlorambucil
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Formula |
C37H55Cl2N7O9S
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 844.86 | ||||
| Lipid-water partition coefficient (xlogp) | 3.20637 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 8 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 12 | |||||
| Rotatable Bond Count (rotbonds) | 27 | |||||