Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02090
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| PDC Name |
Ac-NH-GCASYR-PC4AP-DOX
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
GCASYR
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Peptide Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
PC4AP
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Linker Info | ||||
| Formula |
C83H99N13O37S
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1902.826 | ||||
| Lipid-water partition coefficient (xlogp) | -1.6844 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 17 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 38 | |||||
| Rotatable Bond Count (rotbonds) | 46 | |||||