Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02094
|
|||||
|---|---|---|---|---|---|---|
| PDC Name |
NH2-GCKSYR-C4AP-DOX
|
|||||
| PDC Status |
Investigative
|
|||||
| Structure |
|
|||||
| Peptide Name |
GCKSYR
|
Peptide Info | ||||
| Drug Name |
Doxorubicin
|
Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
|
Target Info | ||||
| Linker Name |
C4AP
|
Linker Info | ||||
| Formula |
C66H86N12O28S
|
|||||
| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 1527.537 | ||||
| Lipid-water partition coefficient (xlogp) | -6.0525 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 20 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 31 | |||||
| Rotatable Bond Count (rotbonds) | 39 | |||||