Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02098
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| PDC Name |
NH2-GRDWQSCMEYKTHN-C4AP-DOX
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
GRDWQSCMEYKTHN
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Peptide Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
C4AP
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Linker Info | ||||
| Formula |
C110H145N25O43S2
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 2569.636 | ||||
| Lipid-water partition coefficient (xlogp) | -10.87 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 35 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 46 | |||||
| Rotatable Bond Count (rotbonds) | 74 | |||||