Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02103
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| PDC Name |
SN38(10)-4-(Ac)CGVQIRGDK
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
CGVQIRGDK
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Peptide Info | ||||
| Receptor Name |
Neuropilin-1 (NRP1)
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Receptor Info | ||||
| Drug Name |
7-Ethyl-10-hydroxycamptothecin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
4-(2Disulfaneylethoxy)-4-oxobutanoic acid
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Linker Info | ||||
| Formula |
C69H98N16O22S2
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 1567.767 | ||||
| Lipid-water partition coefficient (xlogp) | -2.3924 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 16 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 26 | |||||
| Rotatable Bond Count (rotbonds) | 47 | |||||