Receptor Information
General Information of This Receptor
| Receptor ID |
REC00015
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| Receptor Name |
Cathepsin B (CTSB)
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| Gene Name |
CTSB
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| Gene ID | ||||||
| Synonym |
CPSB; APP secretase; Cathepsin B1
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| Sequence |
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
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| 3D Structure | ||||||
| Family |
the peptidase C1 family
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| Function |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins . Cleaves matrix extracellular phosphoglycoprotein MEPE . Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis.
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| Uniprot Entry | ||||||
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Each Peptide-drug Conjuate AND It's Component Related to This Receptor
Full List of The PDC Related to This Receptor
RR
| PDC Info | PDC Name | Drug | Target | Linker |
|---|---|---|---|---|
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RR-BA
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Ursodeoxycholic acid
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Biliverdin reductase A (BLVRA)
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Amide bond
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RR - 2H-1-Benzopyran-6-sulfonic acid, 3,4-dihydro-2,2,5,7,8-pentamethyl conjugate 1
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2H-1-Benzopyran-6-sulfonic acid, 3,4-dihydro-2,2,5,7,8-pentamethyl
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Undisclosed
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Undisclosed
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RR - 2H-1-Benzopyran-6-sulfonic acid, 3,4-dihydro-2,2,5,7,8-pentamethyl conjugate 2
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2H-1-Benzopyran-6-sulfonic acid, 3,4-dihydro-2,2,5,7,8-pentamethyl
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Undisclosed
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Undisclosed
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RR - 3-(Benzyloxy)aniline conjugate
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3-Benzyloxyaniline
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Undisclosed
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Undisclosed
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