Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00032
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| PDC Name |
18F-PSMA-1007
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| Synonyms |
18F-PSMA 1007; (2~{S})-2-[[(2~{S})-6-[[(2~{S})-2-[[4-[[[(2~{S})-2-[[(2~{S})-2-[(6-fluoranylpyridin-3-yl)carbonylamino]-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]methyl]phenyl]carbonylamino]-3-naphthalen-2-yl-propanoyl]amino]-1-oxidanyl-1-oxidanylidene-hexan-2-yl]carbamoylamino]pentanedioic acid; 2093321-18-5; SCHEMBL20180889; PSMA-1007?; 9OT
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
PSMA-617
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Peptide Info | ||||
| Receptor Name |
Glutamate carboxypeptidase 2 (FOLH1)
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Receptor Info | ||||
| Drug Name |
Fluorine-18
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Drug Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
2-(4-(aminomethyl)benzamido)-3-(naphthalen-2-yl)propanoic acid
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Linker Info | ||||
| Peptide Modified Type |
The modification of binding with chemical molecules
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| Modified Segment |
Urea
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| Formula |
C49H55FN8O16
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1031 | ||||
| Lipid-water partition coefficient (xlogp) | 1.7 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 12 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 18 | |||||
| Rotatable Bond Count (rotbonds) | 30 | |||||