Target Information
General Information of This Target
| Target ID |
TAR10052
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|---|---|---|---|---|---|---|
| Target Name |
Human Deoxyribonucleic acid (hDNA)
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Full List of The PDC Related to This Target
Approved
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
177Lu-PSMA-617
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-177
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
68Ga-PSMA-11
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Gallium-68
|
Aminocaproic acid
|
|
|
111In-DTPA-octreotide
|
Octreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Indium-111
|
Amide bond
|
|
|
177Lu-DOTATATE
|
3-Tyr-Octreotate
|
Somatostatin receptor type 1 (SSTR1)
|
Lutetium-177
|
Amide bond
|
|
|
68Ga-DOTATATE
|
3-Tyr-Octreotate
|
Somatostatin receptor type 1 (SSTR1)
|
Gallium-68
|
Amide bond
|
|
|
Copper dotatate Cu-64
|
3-Tyr-Octreotate
|
Somatostatin receptor type 1 (SSTR1)
|
Copper-64
|
Amide bond
|
Phase 3
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
18F vipivotide traxetan
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Fluorine-18
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
99mTc-3PRGD2
|
c(RGDfK)
|
Integrin alpha-V; Integrin beta-3 (ITGAV; ITGB3)
|
Technetium-99m
|
PEG2
|
|
|
68Ga-NODAGA-E[c(RGDyK)]2
|
c(RGDyK)
|
Integrin alpha-V; Integrin beta-3 (ITGAV; ITGB3)
|
Gallium-68
|
NODAGA
|
Phase 2/3
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
68Ga-PSMA-617
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Gallium-68
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
Phase 2
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
90Y-DOTATOC
|
Edotreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Yttrium-90
|
Amide bond
|
|
|
177Lu-PSMA I&T
|
PSMA I&T
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-177
|
PSMA-I&T Linker
|
Phase 1/2
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
[177Lu]Lu-DPI-4452
|
DPI-4452
|
Undisclosed
|
Lutetium-177
|
Ethyl 2-(piperazin-1-yl)acetate
|
Phase 1
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
225Ac-PSMA-617
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Actinium-225
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
68Ga-DOTANOC
|
3-Nal-Octreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Gallium-68
|
Amide bond
|
|
|
Debio-0328
|
DPI-4452
|
Undisclosed
|
Gallium-68
|
Ethyl 2-(piperazin-1-yl)acetate
|
Investigative
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
([α,β-3H]Nal)Lu-PSMA-617
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-175
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
[177Lu]Lu-4
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-177
|
rac-(R)-2-(2-aminoacetamido)-3-(4-(2-(((R)-1-carboxy-2-phenylethyl)amino)-2-oxoethoxy)phenyl)propanoic acid
|
|
|
[177Lu]Lu-7
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-177
|
rac-(R)-2-(2-aminoacetamido)-3-(4-(2-(((R)-1-carboxy-2-phenylethyl)amino)-2-oxoethoxy)phenyl)propanoic acid
|
|
|
[177Lu]Lu-P17-079
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-177
|
Phosphonic Acid Linker
|
|
|
[177Lu]Lu-P17-081
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-177
|
rac-(R)-2-(2-aminoacetamido)-3-(4-(2-(((R)-1-carboxy-2-phenylethyl)amino)-2-oxoethoxy)phenyl)propanoic acid
|
|
|
161Tb-PSMA-617
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Terbium-161
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
175Lu-PSMA-617
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Lutetium-175
|
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
18F-PSMA-1007
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Fluorine-18
|
2-(4-(aminomethyl)benzamido)-3-(naphthalen-2-yl)propanoic acid
|
|
|
68Ga-PSMA HBED-CC
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Gallium-68
|
Aminocaproic acid
|
|
|
Piflufolastat F-18
|
PSMA-617
|
Glutamate carboxypeptidase 2 (FOLH1)
|
Fluorine-18
|
Amide bond
|
|
|
225Ac-DOTATOC
|
Edotreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Actinium-225
|
Amide bond
|
|
|
[18F]AlF-NOTA-octreotide
|
Octreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Fluorine-18
|
Amide bond
|
|
|
99mTc-octreotide
|
Octreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Technetium-99m
|
Amide bond
|
|
|
64Cu-NODAGA-E[c(RGDyK)]2
|
c(RGDyK)
|
Integrin alpha-V; Integrin beta-3 (ITGAV; ITGB3)
|
Copper-64
|
NODAGA
|
|
|
68Ga-DOTA-GIP1234
|
GIP1234
|
Undisclosed
|
Gallium-68
|
2-((2-aminoethyl)sulfonyl)ethane-1-thiol
|
|
|
18F-fallypride
|
Fallypride
|
D(2) dopamine receptor; D(3) dopamine receptor (DRD2; DRD3)
|
Fluorine-18
|
Alkane
|
|
|
Tetrapeptide 30 - Cyclophosphamide conjugate
|
Tetrapeptide 30
|
Undisclosed
|
Cyclophosphamide
|
Undisclosed
|