Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00370
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| PDC Name |
18F vipivotide traxetan
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| PDC Status |
Phase 3
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| Structure |
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| Peptide Name |
PSMA-617
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Peptide Info | ||||
| Receptor Name |
Glutamate carboxypeptidase 2 (FOLH1)
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Receptor Info | ||||
| Drug Name |
Fluorine-18
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Drug Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
(S)-2-(4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanoic acid
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Linker Info | ||||
| Peptide Modified Type |
The modification of binding with chemical molecules
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| Modified Segment |
Urea
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| Formula |
C49H69AlFN9O16
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 1085.120938 | ||||
| Lipid-water partition coefficient (xlogp) | -6.4242 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 9 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 16 | |||||
| Rotatable Bond Count (rotbonds) | 27 | |||||