Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00134
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| PDC Name |
DOX-EMCH-fMLFC
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
DEF
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Peptide Info | ||||
| Receptor Name |
fMet-Leu-Phe receptor (FPR1)
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Receptor Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
N-ε-maleimidocaproic acid hydrazide
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Linker Info | ||||
| Peptide Modified Type |
The modification of binding with chemical macromolecules
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| Ternimal Modification |
C-terminal modification
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| Formula |
C61H78N8O19S2
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1291.466 | ||||
| Lipid-water partition coefficient (xlogp) | 1.021 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 12 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 22 | |||||
| Rotatable Bond Count (rotbonds) | 30 | |||||