Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00320
|
|||||
|---|---|---|---|---|---|---|
| PDC Name |
PVGLIG-paclitaxel
|
|||||
| PDC Status |
Investigative
|
|||||
| Structure |
|
|||||
| Peptide Name |
Hexapeptide
|
Peptide Info | ||||
| Receptor Name |
72 kDa type IV collagenase (MMP2)
|
Receptor Info | ||||
| Drug Name |
Paclitaxel
|
Drug Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
Ester bond
|
Linker Info | ||||
| Formula |
C73H95N7O20
|
|||||
| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1390.592 | ||||
| Lipid-water partition coefficient (xlogp) | 3.4736 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 9 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 21 | |||||
| Rotatable Bond Count (rotbonds) | 27 | |||||