Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00373
|
|||||
|---|---|---|---|---|---|---|
| PDC Name |
WRWRWRWRWK - Doxorubicin conjugate
|
|||||
| PDC Status |
Investigative
|
|||||
| Structure |
|
|||||
| Peptide Name |
WRWRWRWRWK
|
Peptide Info | ||||
| Drug Name |
Doxorubicin
|
Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
|
Target Info | ||||
| Linker Name |
Glutaric acid
|
Linker Info | ||||
| Peptide Modified Type |
Cyclization modification
|
|||||
| Formula |
C120H148N30O24
|
|||||
| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 2394.69 | ||||
| Lipid-water partition coefficient (xlogp) | 1.04998 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 34 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 29 | |||||
| Rotatable Bond Count (rotbonds) | 44 | |||||