Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00374
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| PDC Name |
GFLG - Doxorubicin conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
GFLG
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Peptide Info | ||||
| Receptor Name |
Integrin alpha-V; Integrin beta-3 (ITGAV; ITGB3)
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Receptor Info | ||||
| Drug Name |
Doxorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Formula |
C53H60N6O18
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1069.087 | ||||
| Lipid-water partition coefficient (xlogp) | -1.0353 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 10 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 18 | |||||
| Rotatable Bond Count (rotbonds) | 21 | |||||