Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00632
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| PDC Name |
c(RGDfK) - 2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonamide conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
c(RGDfK)
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Peptide Info | ||||
| Receptor Name |
Integrin alpha-V; Integrin beta-3 (ITGAV; ITGB3)
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Receptor Info | ||||
| Drug Name |
2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonamide
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Drug Info | ||||
| Linker Name |
Undisclosed
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| Peptide Modified Type |
Cyclization modification
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| Formula |
C44H65N9O10S
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 912.124 | ||||
| Lipid-water partition coefficient (xlogp) | 0.87106 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 8 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 12 | |||||
| Rotatable Bond Count (rotbonds) | 14 | |||||