Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00637
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| PDC Name |
c(RGDfK) - Ureidopyrimidinone conjugate 3
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
c(RGDfK)
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Peptide Info | ||||
| Receptor Name |
Integrin alpha-V; Integrin beta-3 (ITGAV; ITGB3)
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Receptor Info | ||||
| Drug Name |
Ureidopyrimidinone
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Drug Info | ||||
| Linker Name |
PEG
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Linker Info | ||||
| Peptide Modified Type |
Cyclization modification
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| Formula |
C61H100N16O19
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1361.564 | ||||
| Lipid-water partition coefficient (xlogp) | -1.42788 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 15 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 20 | |||||
| Rotatable Bond Count (rotbonds) | 48 | |||||