Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_00692
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| PDC Name |
Glutamic acid oligopeptide 2 - Ibuprofen conjugate 3
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Glutamic acid oligopeptide 2
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Peptide Info | ||||
| Drug Name |
Naproxen
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Drug Info | ||||
| Therapeutic Target |
Prostaglandin G/H synthase 1 (COX-1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Formula |
C39H49N5O18
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 875.838 | ||||
| Lipid-water partition coefficient (xlogp) | -0.2155 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 11 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 12 | |||||
| Rotatable Bond Count (rotbonds) | 28 | |||||