Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01088
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| PDC Name |
ErbB-2-binding peptide - Daunorubicin conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
ErbB-2-binding peptide
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Peptide Info | ||||
| Drug Name |
Daunorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Glutaric acid
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Linker Info | ||||
| Formula |
C72H91N11O21
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1446.576 | ||||
| Lipid-water partition coefficient (xlogp) | -0.035 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 16 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 23 | |||||
| Rotatable Bond Count (rotbonds) | 29 | |||||