Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_01441
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| PDC Name |
Polyarginin 2 - Daunorubicine conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Polyarginin 2
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Peptide Info | ||||
| Drug Name |
Daunorubicin
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Succinic Acid
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Linker Info | ||||
| Formula |
C67H106N26O18
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 1563.749 | ||||
| Lipid-water partition coefficient (xlogp) | -7.05968 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 30 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 24 | |||||
| Rotatable Bond Count (rotbonds) | 44 | |||||