Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02120
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| PDC Name |
Gefitinib LARLLT conjugate a
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
D4
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Peptide Info | ||||
| Receptor Name |
Pro-epidermal growth factor (EGF)
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Receptor Info | ||||
| Drug Name |
Gefitinib
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Drug Info | ||||
| Therapeutic Target |
Epidermal growth factor receptor (EGFR)
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Target Info | ||||
| Linker Name |
Succinic Acid
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Linker Info | ||||
| Formula |
C57H86ClFN14O12
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1213.852 | ||||
| Lipid-water partition coefficient (xlogp) | 2.4538 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 11 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 16 | |||||
| Rotatable Bond Count (rotbonds) | 35 | |||||