Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02121
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| PDC Name |
Gefitinib LARLLT conjugate b
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
D4
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Peptide Info | ||||
| Receptor Name |
Pro-epidermal growth factor (EGF)
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Receptor Info | ||||
| Drug Name |
Gefitinib
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Drug Info | ||||
| Therapeutic Target |
Epidermal growth factor receptor (EGFR)
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Target Info | ||||
| Linker Name |
Glutaric acid
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Linker Info | ||||
| Formula |
C58H88ClFN14O12
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1227.879 | ||||
| Lipid-water partition coefficient (xlogp) | 2.8439 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 11 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 16 | |||||
| Rotatable Bond Count (rotbonds) | 36 | |||||