Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02132
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| PDC Name |
ANG1009
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Angiopep-2
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Peptide Info | ||||
| Receptor Name |
Prolow-density lipoprotein receptor-related protein 1; Low-density lipoprotein receptor-related protein 2 (LRP1; LRP2)
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Receptor Info | ||||
| Drug Name |
Etoposide
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Drug Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
Succinic Acid
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Linker Info | ||||
| Formula |
C203H251N29O76
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| #Ro5 Violations (Lipinski): 5 | Molecular Weight | 4313.368 | ||||
| Lipid-water partition coefficient (xlogp) | -6.2345 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 41 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 75 | |||||
| Rotatable Bond Count (rotbonds) | 111 | |||||