Peptide-drug Conjugate Information
General Information of This Peptide-drug Conjugate (PDC)
| PDC ID |
PDC_02116
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| PDC Name |
Pentagastrin-(+)-duocarmycin SA conjugate
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| PDC Status |
Investigative
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| Structure |
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| Peptide Name |
Pentagastrin
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Peptide Info | ||||
| Receptor Name |
Gastrin-releasing peptide receptor (GRPR)
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Receptor Info | ||||
| Drug Name |
Duocarmycin Sa
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Drug Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
Amide bond
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Linker Info | ||||
| Formula |
C58H62ClN9O13S
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| #Ro5 Violations (Lipinski): 4 | Molecular Weight | 1160.704 | ||||
| Lipid-water partition coefficient (xlogp) | 4.7742 | |||||
| Hydrogen Bond Donor Count (hbonddonor) | 10 | |||||
| Hydrogen Bond Acceptor Count (hbondacc) | 13 | |||||
| Rotatable Bond Count (rotbonds) | 26 | |||||