Target Information
General Information of This Target
| Target ID |
TAR10016
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| Target Name |
Human Deoxyribonucleic acid (hDNA)
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| Function |
Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids.
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Full List of The PDC Related to This Target
Approved
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
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Melflufen
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p-Fluorophenylalanine
|
Aminopeptidases
|
Melphalan
|
Acetic acid
|
Investigative
| PDC Info | PDC Name | Peptide | Receptor | Drug | Linker |
|---|---|---|---|---|---|
|
TFα-peptide-duocarmycin conjugate
|
TFα-peptide
|
Thomsen-Friedenreich antigen (TFa)
|
Duocarmycin Sa
|
Val-Cit
|
|
|
P4-bendamustine
|
p4
|
Undisclosed
|
Bendamustine
|
Gamma-Aminobutyric Acid
|
|
|
P4-Bend-PEG-AuNP
|
p4
|
Undisclosed
|
Bendamustine
|
Gamma-Aminobutyric Acid
|
|
|
P4-melphalan
|
p4
|
Undisclosed
|
Melphalan
|
Amide bond
|
|
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P4-Melph-PEG-AuNP
|
p4
|
Undisclosed
|
Melphalan
|
Amide bond
|
|
|
SG3511
|
NALRDQTGLKNPVQLARAVC
|
Integrin alpha-V; Integrin beta-6 (ITGAV; ITGB6)
|
Pyrrolobenzodiazepine (PBD) dimer
|
Val-Ala
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SG3299
|
A20FMDV2
|
Integrin alpha-V; Integrin beta-6 (ITGAV; ITGB6)
|
Pyrrolobenzodiazepine (PBD) dimer
|
Val-Ala
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|
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P6-bendamustine
|
p6
|
Undisclosed
|
Bendamustine
|
Gamma-Aminobutyric Acid
|
|
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P6-melphalan
|
p6
|
Undisclosed
|
Melphalan
|
Amide bond
|
|
|
67Ga-MMC(TMZ)-TOC
|
3-Tyr-Octreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Temozolomide
|
Amide bond
|
|
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MMC(TMZ)-TOC
|
3-Tyr-Octreotide
|
Somatostatin receptor type 1 (SSTR1)
|
Temozolomide
|
Amide bond
|
|
|
MP-P5
|
P5
|
Undisclosed
|
Mesoporphyrin IX
|
Amide bond
|
|
|
MP-P6
|
P6
|
Undisclosed
|
Mesoporphyrin IX
|
Amide bond
|
|
|
MP-P1
|
P1
|
Undisclosed
|
Mesoporphyrin IX
|
Amide bond
|
|
|
MP-P2
|
P2
|
Undisclosed
|
Mesoporphyrin IX
|
Amide bond
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Pentagastrin-(+)-duocarmycin SA conjugate
|
Pentagastrin
|
Gastrin-releasing peptide receptor (GRPR)
|
Duocarmycin Sa
|
Amide bond
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