Receptor Information
General Information of This Receptor
| Receptor ID |
REC00059
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|---|---|---|---|---|---|---|
| Receptor Name |
Integrin
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| Function |
Integrins are a large family of cell surface receptors that play crucial roles in cell adhesion, signaling, and interaction with the extracellular matrix (ECM). They are transmembrane proteins composed of (alpha) and (beta) subunits, which form heterodimers.
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Each Peptide-drug Conjuate AND It's Component Related to This Receptor
Full List of The PDC Related to This Receptor
EETI-2.5Z
| PDC Info | PDC Name | Drug | Target | Linker |
|---|---|---|---|---|
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EETI-2.5Z-amide -gemcitabine
|
Gemcitabine
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Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
|
Alkyne-Triazole
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EETI-2.5Z-carbamate -gemcitabine
|
Gemcitabine
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Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
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(3-(1H-1,2,3-triazol-4-yl)propyl)carbamic acid
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EETI-2.5Z-ester-gemcitabine
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Gemcitabine
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Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
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3-(1H-1,2,3-Triazol-4-yl)propanoic acid
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EETI-2.5Z-Val-Ala-PAB-gemcitabine
|
Gemcitabine
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Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
|
rac-4-((R)-2-((R)-2-(3-(1H-1,2,3-triazol-4-yl)propanamido)-3-methylbutanamido)propanamido)benzyl hydrogen carbonate
|
RGD
| PDC Info | PDC Name | Drug | Target | Linker |
|---|---|---|---|---|
|
Linear arginineglycineaspartic acid (RGD) - Ibuprofen conjugate 1
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Ibuprofen
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Prostaglandin G/H synthase 2 (PTGS2)
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Amide bond
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Linear arginineglycineaspartic acid (RGD) - Ibuprofen conjugate 2
|
Ibuprofen
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Prostaglandin G/H synthase 2 (PTGS2)
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Aminocaproic acid
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Linear arginineglycineaspartic acid (RGD) - Naproxen conjugate 3
|
Naproxen
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Prostaglandin G/H synthase 1 (COX-1)
|
Amide bond
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Linear arginineglycineaspartic acid (RGD) - Naproxen conjugate 4
|
Naproxen
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Prostaglandin G/H synthase 1 (COX-1)
|
Aminocaproic acid
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