Receptor Information
General Information of This Receptor
| Receptor ID |
REC00027
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| Receptor Name |
Neuropeptide Y receptor type 1 (NPY1R)
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| Gene Name |
NPY1R
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| Gene ID | ||||||
| Synonym |
NPYR; NPYY1
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| Sequence |
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS KTSLKQASPVAFKKINNNDDNEKI
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| 3D Structure | ||||||
| Family |
the G-protein coupled receptor 1 family
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| Function |
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.
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| Uniprot Entry | ||||||
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Each Peptide-drug Conjuate AND It's Component Related to This Receptor
Full List of The PDC Related to This Receptor
[K4(C-βA-),F7,L17,P34]-hNPY
| PDC Info | PDC Name | Drug | Target | Linker |
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Tesaglitazar-[F7, P34]-NPY
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Tesaglitazar
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Peroxisome proliferator-activated receptor alpha (PPARA)
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GFLG
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Tubugi-1-NPY
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Tubugis
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Microtubule (MT)
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Disulfide bond
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[K4,F7,K22,P34]-NPY
| PDC Info | PDC Name | Drug | Target | Linker |
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PDC-5a
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Methotrexate
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Reduced folate transporter (SLC19A1)
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Amide bond
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PDC-5b
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Methotrexate
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Reduced folate transporter (SLC19A1)
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GFLG
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PDC-5c
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Methotrexate
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Reduced folate transporter (SLC19A1)
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Amide bond
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PDC-5d
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Methotrexate
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Reduced folate transporter (SLC19A1)
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GFLG
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Cytolysin[F7,P34]-NPY bioconjugate
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Cytolysin-dithiopyridine
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Undisclosed
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Disulfide bond
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